Searchable abstracts of presentations at key conferences on calcified tissues

ba0003pp89 | Bone development/growth and fracture repair | ECTS2014

Zoledronate prevents lactation induced loss of bone strength and micro-architecture

Wendelboe Mette Hoegh , Thomsen Jesper Skovhus , Bruel Annemarie

Objective: In rodents, lactation is associated with a considerable and very rapid bone loss, which almost completely recovers after weaning. The aim of the present study was to investigate whether the bisphosphonate zoledronate (Zln) inhibits lactation induced bone loss during lactation. In addition, to study if Zln interferes with recovery of bone mass after lactation has ceased.Materials and methods: 70 NMRI mice were divided into the following groups:...